DOI: 10.1002/iju5.12704 ISSN: 2577-171X

A seed link connector protruding into the bladder formed a bladder stone

Shuhei Aoyama, Kouji Izumi, Tomoyuki Makino, Renato Naito, Suguru Kadomoto, Hiroaki Iwamoto, Hiroshi Yaegashi, Shohei Kawaguchi, Kazuyoshi Shigehara, Takahiro Nohara, Atsushi Mizokami
  • Urology


Low‐dose‐rate brachytherapy is performed for localized prostate cancer. We report the first case of a bladder stone encompassing the seed migrated into the bladder in a patient treated with low‐dose‐rate brachytherapy.

Case presentation

A man was diagnosed with prostate cancer and underwent low‐dose‐rate brachytherapy. After 2 months, dysuria occurred, and ultrasonography revealed a needle‐shaped high‐intensity protruding from the prostate into the bladder. Cystoscopy examination found a seed link connector. With the possibility of natural dissolution of the seed link, careful observation was chosen. However, 16 months later, hematuria occurred, and an X‐ray revealed a bladder stone encompassing the seed. Compared with the X‐ray right after seeding, the seed located near the right bladder neck had fallen. The seed was removed by transurethral bladder lithotripsy.


Seeds should be carefully located within the prostate, otherwise a bladder stone may be formed encompassing the seed.

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