SP6.1 Short-term and long-term remission of Type 2 diabetes mellitus after Sleeve Gastrectomy (SG) vs One-Anastomosis Gastric Bypass (OAGB) vs Roux-en-Y Gastric Bypass (RYGB): A Narrative Literature ReviewVignesh Balasubaramaniam
The three most widely performed bariatric surgeries are RYGB, SG, and OAGB. Aside from the benefits of weight loss, current findings suggest that these procedures can also induce remission of T2DM. There are limited data that directly compare these three procedures. This study aims to compare the short-term and long-term remission of T2DM after RYGB, SG, and OAGB.
Three databases (Embase, PubMed, and Cochrane) were searched for randomised controlled trials, systematic reviews, meta-analyses, retrospective studies, and literature reviews that compared the effects of RYGB, SG, and OAGB on T2DM remission. The studies were published over a ten-year period (2012 - 2022). Only patients with T2DM and who had primary bariatric surgery were included.
After applying the inclusion and exclusion criteria, six articles were included in the review. It was found that OAGB had superior T2DM remission and weight loss in the short-term and long-term follow-up. RYGB was noted to have the highest complication rate when compared to SG and OAGB. Moreover, in one of the studies, patients who were not taking insulin had a higher remission rate than those taking insulin.
This narrative literature review confirms the existing data that all three bariatric surgeries induce remission of T2DM. With the limited studies available that compared all three procedures, OAGB was found to be the superior procedure in terms of weight loss and inducing remission of T2DM. It is also worth noting that there are other independent predictive factors that have an impact on T2DM remission.