DOI: 10.1177/15563316231193753 ISSN:

Relationship of Chronic Systemic Inflammation to Both Chronic Lifestyle: The Case for Lifestyle Medicine for Osteoarthritis

Heidi Prather, Jennifer Cheng
  • Orthopedics and Sports Medicine
  • Surgery

Systemic inflammation is a root cause of lifestyle-related chronic diseases and may also play a role in the development and progression of osteoarthritis (OA). Lifestyle medicine seeks to treat, prevent, and reverse lifestyle-related chronic disease via 6 pillars: nutrition, sleep health, stress management, physical activity, social connections, and risky behavior avoidance/reduction. This article presents a review of the literature in which we assess the connections between the 6 pillars of lifestyle medicine, chronic systemic inflammation, and OA. We also discuss the whole-person approach that lifestyle medicine interventions can provide to reduce chronic systemic inflammation and affect the development or progression of OA.

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