DOI: 10.1093/bjs/znad258.138 ISSN:

730 An Audit of Antibiotic Prescription in Acute Pancreatitis

A Othman, M Ben Abdalla, T Baston, K McComb, M Barghash, J Sadic
  • Surgery



To assess the prescription of antibiotics in the management of acute pancreatitis in North Manchester General Hospital and to determine adherence to NICE Guidelines (NG104).


Retrospective analysis of patients admitted to North Manchester General Hospital, with a diagnosis of acute pancreatitis, between 1st January 2021 and 31st December 2021. Analysis performed by assessing case notes, electronic Prescribing and Medicines Administration (ePMA) system, radiological imaging, and blood test results. The Atlanta Classification was used to define the inclusion criteria for acute pancreatitis.


A total of 98 patients were diagnosed with acute pancreatitis. Subsequently, 11 patients were excluded due to insufficient evidence to support their diagnosis. 65.5% of patients were prescribed antibiotics on admission. 12.1% of patients were prescribed antibiotics for necrosis, 12.14% for concurrent cholecystitis and 33.4% were prescribed antibiotics without indication.


Poor compliance with national guidelines on the recommended management of acute pancreatitis. Audit results and the recommended NICE Guidelines were disseminated to all members of the General Surgery team with further consolidation at the local governance meeting to improve knowledge and streamline practice.

More from our Archive