Aspergillus spp. renal arteritis after kidney transplantation: A reappraisal
Romain Gueneau, Chloé Giret, Emmanuel Lafont, Matthieu Buchler, Hélène Longuet, Marie‐Christine Machet, Nadia Ghazzar, Fanny Lanternier, Olivier Lortholary- Infectious Diseases
- Transplantation
Abstract
Background
Aspergillus spp. is an uncommon and life‐threatening cause of transplantrenal artery pseudoaneurysm after kidney transplantation.
Case
We report the case of a 62‐year‐old woman who underwent kidney transplantation 10 months before and presented a 7‐cm asymptomatic transplant renal artery pseudoaneurysm. Transplanted kidney and pseudoaneurysm were surgically removed in emergency. Renal graft, urine, and pseudoaneurysm cultures grew Aspergillus flavus. She recovered after 12 months of antifungal therapy.
Literature review
To date 14 cases of Aspergillus spp. renal arteritis after kidney transplantation have been published, including 50% Aspergillus flavus arteritis. Vast majority were diagnosed within 90 days after transplantation (73%). Despite allograft nephrectomy and antifungal therapy, mortality rate was high (33%).