DOI: 10.1039/d3ob01283b ISSN: 1477-0520

Facile preparation of polycyclic halogen-substituted 1,2,3-triazoles by using intramolecular Huisgen cycloaddition

Kazuki Kobayashi, Nozomi Kasakura, Seiya Kikukawa, Shota Matsumoto, Satoru Karasawa, Takeshi Hata
  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

1-(ω-Azidoalkyl)-2-(2,2-dihalovinyl)arenes afforded tricyclic 5-halo-1,2,3-triazoles via intramolecular Huisgen cycloaddition. Based on the remaining bromo groups, carbon elongation gave polycyclic compounds and a pentacyclic fluorescent compound.

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