DOI: 10.1002/cncr.35245 ISSN: 0008-543X

Challenges in clinical trials for high‐risk but curable prostate cancer

Tanya Barauskas Dorff, Alan H. Bryce
  • Cancer Research
  • Oncology

Clinical trials studying neoadjuvant and adjuvant therapy around prostatectomy for patients with high‐risk prostate cancer have faced multiple challenges. Patients who have a very good response to neoadjuvant therapy may not wish to continue to adjuvant treatment, and prostate‐specific antigen–based end points are difficult to interpret because of variations in testosterone recovery.

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