DOI: 10.1002/cncr.35245 ISSN: 0008-543X
Challenges in clinical trials for high‐risk but curable prostate cancer
Tanya Barauskas Dorff, Alan H. Bryce- Cancer Research
- Oncology
Clinical trials studying neoadjuvant and adjuvant therapy around prostatectomy for patients with high‐risk prostate cancer have faced multiple challenges. Patients who have a very good response to neoadjuvant therapy may not wish to continue to adjuvant treatment, and prostate‐specific antigen–based end points are difficult to interpret because of variations in testosterone recovery.