DOI: 10.1039/d3qo01877f ISSN: 2052-4129

Atroposelective synthesis of N–N axially chiral pyrrolyl(aza)-quinolinone by de novo ring formation

Qiwen Huang, Yanze Li, Cun Yang, Wendan Wu, Jingjie Hai, Xinyao Li
  • Organic Chemistry

A chiral phosphoric acid-catalyzed Paal–Knorr reaction was achieved for constructing axially chiral pyrrolyl(aza)quinolinones with ‘6–5’-membered rings as a new family member of N–N atropisomers.

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