Hector Sanchez, George A. O’Toole, Brent Berwin

Assessment of the Glycan-Binding Profile of Pseudomonas aeruginosa PAO1

  • Infectious Diseases
  • Cell Biology
  • Microbiology (medical)
  • Genetics
  • General Immunology and Microbiology
  • Ecology
  • Physiology

P. aeruginosa cells bind to a variety of glycans as part of their interaction with host cells, and a number of P. aeruginosa -encoded receptors and target ligands have been described that allow this microbe to bind to such glycans. Here, we extend this work by studying the glycans used by P. aeruginosa PAO1 cells to bind to phagocytic cells and by using a glycan array to characterize the suite of such molecules that can facilitate host cell binding by this microbe.

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