DOI: 10.1002/jhet.70088 ISSN: 0022-152X
A Solvent‐Free One‐Pot Synthesis of Ethyl 4‐Oxo‐3,4‐Dihydro Quinazoline‐2‐Carboxylates Utilizing N‐(2‐Aminobenzoyl) Benzotriazoles
Nasir Ahmad Heravi, Sultan Funda Ekti, İlhami ÇelikABSTRACT
A new solvent‐free one‐pot method for the synthesis of ethyl 4‐oxo‐3,4‐dihydroquinazoline‐2‐carboxylates using N‐(2‐aminobenzoyl) benzotriazoles was developed. In this method, ethyl 4‐oxo‐3,4‐dihydroquinazoline‐2‐carboxylates were obtained in good yields (20%–85%) by the reaction of N‐(2‐amino benzoyl) benzotriazoles with diethyl oxalate and ammonium acetate in the absence of solvent.