3-/3,5-Styryl-Substituted BODIPY with N-Bridged Annulation: Synthesis and Spectroscopic properties

The development of organic dyes with high fluorescence quantum yield (FLQY) and tunable emission has significant application potential in biomedicine and material science. Here, we report four N-bridged annulation BODIPY dyes, which introduce styryl units at the 3- and 3,5-positions of the BODIPY core via Knoevenagel condensation reaction, showing high FLQY and tunable fluorescence. The intrinsic relationship between structure and properties is comprehensively analyzed through density functional theory (DFT) calculations, which is crucial for the rational design of new BODIPY dyes with desired properties for specific applications.