DOI: 10.13005/ojc/390433 ISSN:

Ytterbium(III) Chloride: A Superior Reagent for the Synthesis of 4-Chloro-5, 6-Dihydro-2H-Pyran Derivatives via Cyclization of Epoxides and Homopropargyl Alcohols

Tirukovela Manjula, Jeyanthi Arasan
  • Drug Discovery
  • Environmental Chemistry
  • Biochemistry
  • General Chemistry

Prins type cyclization reaction of epoxides and homopropargyl alcohols in the presence of Ytterbium trichloride results in high yields of the corresponding dihydropyran derivatives under mild conditions.

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