DOI: 10.3390/molecules28166139 ISSN:
Tuning Benzylic C−H Functionalization of (Thio)xanthenes with Electrochemistry
Changji Wang, Na Yang, Chao Li, Jian He, Hongji Li- Chemistry (miscellaneous)
- Analytical Chemistry
- Organic Chemistry
- Physical and Theoretical Chemistry
- Molecular Medicine
- Drug Discovery
- Pharmaceutical Science
Here, we report a tunable electrochemical benzylic C−H functionalization of (thio)xanthenes with terminal alkynes and nitriles in the absence of any catalyst or external chemical oxidant. The benzylic C−H functionalization can be well controlled by varying the electrochemical conditions, affording the specific coupling products via C−C and C−N bond formation.