The incredible story of ophiobolin A and sphaeropsidin A: two fungal terpenes from wilt-inducing phytotoxins to promising anticancer compounds

doi:10.1039/d3np00035d

DOI: 10.1039/d3np00035d ISSN: 0265-0568

The incredible story of ophiobolin A and sphaeropsidin A: two fungal terpenes from wilt-inducing phytotoxins to promising anticancer compounds

Antonio Evidente

Organic Chemistry
Drug Discovery
Biochemistry

This review describes the chemistry, biosynthesis, and biological activity of ophiobolin A and sphaeropsidin A, two phytotoxic terpenes with potential anticancer activity, and that of their natural analogues and derivatives.

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