DOI: 10.1039/d3ra05330j ISSN:
Synthesis of amantadine clubbed N-aryl amino thiazoles as potent urease, α-amylase & α-glucosidase inhibitors, kinetic and molecular docking studies
Fatima Tuz Zahra, Aamer Saeed, Atteeque Ahmed, Hammad Ismail, Muhammad Umar Ijaz, Fernando Albericio- General Chemical Engineering
- General Chemistry
A series of ten novel compounds were synthesized by incorporating a 1,3 thiazole core into amantadine and their structures were validated using different analytical and spectral methods such as FTIR, EI-MS, 1H NMR, and 13C NMR.