DOI: 10.1177/03000605231195161 ISSN:

Successful anesthesia management with inhalation anesthesia in Rosai–Dorfman disease: a case report

Xinlei Zhang, Xiangjun Zhou, Hanjie Liu, Dezhi Li, Song Liu, Yu Lu
  • Biochemistry (medical)
  • Cell Biology
  • Biochemistry
  • General Medicine

Rosai–Dorfman disease (RDD) is a rare, benign, non-Langerhans cell histiocytic proliferative disease. RDD with central nervous system involvement is extremely rare. Surgical excision is generally regarded as the appropriate treatment of choice for this disease, especially when the lesion causes neurological compression. RDD can be accompanied by systemic symptoms, such as malaise, fever, weight change, leukocytosis, anemia, and hormonal disturbance, which may be challenging during general management. Little is known regarding peri-anesthesia management of this rare disease. We report a case of a patient in his 20s who had recurrent RDD and had general anesthesia with perioperative management. He was obese and hepatic insufficiency. This case report adds to the literature regarding the perioperative anesthetic management of RDD with central nervous system involvement.

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