DOI: 10.1039/d3ra02521g ISSN: 2046-2069
Solubility determination, dissolution properties and solid transformation of resmetirom (form A) in heptane and seven alcohols
Chang Liu, Yue Xu, Haikuan Yuan, Guangxin Tian, Xiaolan Qin, Boxuan Lou, Xijian Liu, Lijuan Zhang, Jie Lu- General Chemical Engineering
- General Chemistry
The solubility of resmetirom (form A) was first systematically acquired in some solvents from 273.15 K to 333.15 K. And a high-precision quantification method was established to study the transformation process between form A and solvates.