DOI: 10.3390/nano13152224 ISSN: 2079-4991

Functional MOF-Based Materials for Environmental and Biomedical Applications: A Critical Review

Maria-Anna Gatou, Ioanna-Aglaia Vagena, Nefeli Lagopati, Natassa Pippa, Maria Gazouli, Evangelia A. Pavlatou
  • General Materials Science
  • General Chemical Engineering

Over the last ten years, there has been a growing interest in metal–organic frameworks (MOFs), which are a unique category of porous materials that combine organic and inorganic components. MOFs have garnered significant attention due to their highly favorable characteristics, such as environmentally friendly nature, enhanced surface area and pore volume, hierarchical arrangements, and adjustable properties, as well as their versatile applications in fields such as chemical engineering, materials science, and the environmental and biomedical sectors. This article centers on examining the advancements in using MOFs for environmental remediation purposes. Additionally, it discusses the latest developments in employing MOFs as potential tools for disease diagnosis and drug delivery across various ailments, including cancer, diabetes, neurological disorders, and ocular diseases. Firstly, a concise overview of MOF evolution and the synthetic techniques employed for creating MOFs are provided, presenting their advantages and limitations. Subsequently, the challenges, potential avenues, and perspectives for future advancements in the utilization of MOFs in the respective application domains are addressed. Lastly, a comprehensive comparison of the materials presently employed in these applications is conducted.

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