DOI: 10.1146/annurev.biophys.26.1.373 ISSN:

SINGLE-PARTICLE TRACKING:Applications to Membrane Dynamics

Michael J. Saxton, Ken Jacobson
  • Structural Biology
  • Biophysics

▪ Abstract  Measurements of trajectories of individual proteins or lipids in the plasma membrane of cells show a variety of types of motion. Brownian motion is observed, but many of the particles undergo non-Brownian motion, including directed motion, confined motion, and anomalous diffusion. The variety of motion leads to significant effects on the kinetics of reactions among membrane-bound species and requires a revision of existing views of membrane structure and dynamics.

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