DOI: 10.1128/mmbr.64.3.548-572.2000 ISSN:
Resistance of Bacillus Endospores to Extreme Terrestrial and Extraterrestrial Environments
Wayne L. Nicholson, Nobuo Munakata, Gerda Horneck, Henry J. Melosh, Peter Setlow- Molecular Biology
- Microbiology
- Infectious Diseases
SUMMARY
Endospores of Bacillus spp., especially Bacillus subtilis, have served as experimental models for exploring the molecular mechanisms underlying the incredible longevity of spores and their resistance to environmental insults. In this review we summarize the molecular laboratory model of spore resistance mechanisms and attempt to use the model as a basis for exploration of the resistance of spores to environmental extremes both on Earth and during postulated interplanetary transfer through space as a result of natural impact processes.