DOI: 10.1039/d3ra03954d ISSN: 2046-2069
Mol-Zero-GAN: zero-shot adaptation of molecular generative adversarial network for specific protein targets
Ravipas Aphikulvanich, Natapol Pornputtapong, Duangdao Wichadakul- General Chemical Engineering
- General Chemistry
A framework that optimizes the drug generative adversarial network (GAN) to produce drugs targeting specific proteins, while preserving drug-likeness using Bayesian optimization and singular value decomposition (SVD).