Investigation of human papilloma virus frequency in pregnant women
Serap Topkara, Sadun Sucu, Anil Turhan Cakir, Muge Harma, Mehmet Ibrahim Harma- Obstetrics and Gynecology
Abstract
Objective
The aim of this study was to determine the frequency of human papillomavirus (HPV), HPV types, and the association with age, pregnancy, and childbirth in pregnant women.
Method
Four hundred and forty‐eight pregnant women who visited our clinic were enrolled in the study. Polymerase chain reaction was used to determine HPV DNA and typing by cervical smear in the initial applications of patients with detailed history. Statistical Package for the Social Sciences (SPSS) 13.0 was used to analyze the data.
Results
HPV DNA was positive in 26 (5.8%) of 448 patients who participated in the study. High‐risk HPV types were detected in 77% of HPV‐positive cases and low‐risk HPV types in 23% of cases. Only one HPV type was detected in 13 patients (50%), while multiple HPV types were detected in 13 patients (50%) of the HPV‐positive cases. A significant negative association was found between gravidity and positivity of HPV DNA. HPV is more common in women with lower parity and gravidity.
Conclusion
Studies conducted in different populations in different regions of Turkey have shown that the incidence of HPV in women ranges from 2.2% to 26%. In our study, the incidence of HPV DNA in pregnant women was 5.8%. It was found that there was an inverse relationship between parity and HPV DNA positivity. The HPV DNA positivity decreased with the number of births.