AbstractObjectivesThe 2018 United Network for Organ Sharing allocation policy change has led to a significant increase in the use of mechanical circulatory support devices in patients listed for orthotopic heart transplantation. However, there has been a paucity of data regarding the newest generation Impella 5.5, which received FDA approval in 2019.MethodsThe United Network for Organ Sharing registry was queried for all adults awaiting orthotopic heart transplantation who received Impella 5.5 support during their listing period. Waitlist, device, and early post‐transplant outcomes were assessed.ResultsA total of 464 patients received Impella 5.5 support during their listing period with a median waitlist time of 19 days. Among them, 402 (87%) patients were ultimately transplanted, with 378 (81%) being directly bridged to transplant with the device. Waitlist death (7%) and clinical deterioration (5%) were the most common reasons for waitlist removal. Device complications and failure were uncommon (<5%). The most common post‐transplant complication was acute kidney injury requiring dialysis (16%). Survival at 1‐year post‐transplant survival was 89.5%.ConclusionSince its approval, the Impella 5.5 has been increasingly used as a bridge to transplant. This analysis demonstrates robust waitlist and post‐transplant outcomes with minimal device‐related and postoperative complications.

More from our Archive

• DOI: 10.1093/ndt/gfad142 2023

  Sepsis-associated acute kidney injury—treatment standard

  Alexander Zarbock, Jay L Koyner, Hernando Gomez, Peter Pickkers, Lui Forni, Mitra K Nadim, Samira Bell, Michael Joannidis, Kianoush Kashani, Neesh Pannu, Melanie Meersch, Thiago Reis, Thomas Rimmelé, Sean M Bagshaw, Rinaldo Bellomo, Vicenzo Cantaluppi, Akash Deep, Silvia De Rosa, Xose Fernandez-Perez, Faeq Husain-Syed, Sandra L Kane-Gill, Yvelynne Kelly, Ravindra L Mehta, Patrick T Murray, Marlies Ostermann, John Prowle, Zaccaria Ricci, Emily J See, Antoine Schneider, Danielle E Soranno, Ashita Tolwani, Gianluca Villa, Claudio Ronco,

• DOI: 10.1111/ctr.15066 2023

  Impella 5.5 as a bridge to heart transplantation: Waitlist outcomes in the United States

  Marisa Cevasco, Max Shin, William Cohen, Mark R. Helmers, Noah Weingarten, David Rekhtman, Joyce W. Wald, Amit Iyengar

• DOI: 10.1093/ndt/gfad146 2023

  IgA nephropathy in adults—treatment standard

  Patrick J Gleeson, Michelle M O'Shaughnessy, Jonathan Barratt

• DOI: 10.1093/ndt/gfad140 2023

  The complement system in IgAN: mechanistic context for therapeutic opportunities

  Anna Duval, Sophie Caillard, Véronique Frémeaux-Bacchi

• DOI: 10.1097/lvt.0000000000000210 2023

  Inhibition of SK2 and ER stress ameliorated inflammation and apoptosis in liver ischemia-reperfusion injury

  Yiya Jiang, Zhaoshuai Huang, Xianpeng Li, Liuzhi Zhou, Xiuping Zhu, Feng Chen, Yanjun Shi

• DOI: 10.1097/tp.0000000000004712 2023

  Urine CXCL10 to Assess BK Polyomavirus Replication After Kidney Transplantation

  Jana Haller, Matthias Diebold, Karoline Leuzinger, Caroline Wehmeier, Joelle Handschin, Patrizia Amico, Patricia Hirt-Minkowski, Jürg Steiger, Michael Dickenmann, Hans H. Hirsch, Stefan Schaub

• DOI: 10.1097/tp.0000000000004720 2023

  The Accuracy of Nonstandardized MELD/PELD Score Exceptions in the Pediatric Liver Allocation System

  Daniel J. Ahn, Sharon Zeng, Kenley M. Pelzer, Rolf N. Barth, Amy Gallo, William F. Parker

• DOI: 10.2215/cjn.0000000000000223 2023

  Ferric Carboxymaltose in Iron-Deficient Patients with Hospitalized Heart Failure and Reduced Kidney Function

  Iain C. Macdougall, Piotr Ponikowski, Austin G. Stack, David C. Wheeler, Stefan D. Anker, Javed Butler, Gerasimos Filippatos, Udo-Michael Göhring, Bridget-Anne Kirwan, Vasuki Kumpeson, Marco Metra, Giuseppe Rosano, Frank Ruschitzka, Peter van der Meer, Sandra Wächter, Ewa A. Jankowska

• DOI: 10.2215/cjn.0000000000000244 2023

  Treatment Guidelines for Hyponatremia

  Richard H. Sterns, Helbert Rondon-Berrios, Horacio J. Adrogué, Tomas Berl, Volker Burst, David M. Cohen, Mirjam Christ-Crain, Martin Cuesta, Guy Decaux, Michael Emmett, Aoife Garrahy, Fabrice Gankam-Kengne, John K. Hix, Ewout J. Hoorn, Kamel S. Kamel, Nicolaos E. Madias, Alessandro Peri, Julie Refardt, Mitchell H. Rosner, Mark Sherlock, Stephen M. Silver, Alain Soupart, Chris J. Thompson, Joseph G. Verbalis,

• DOI: 10.1111/ctr.15077 2023

  Percentage of low attenuation area on computed tomography detects chronic lung allograft dysfunction, especially bronchiolitis obliterans syndrome, after bilateral lung transplantation

  Yujiro Kubo, Seiichiro Sugimoto, Toshio Shiotani, Kei Matsubara, Kohei Hashimoto, Shin Tanaka, Kazuhiko Shien, Ken Suzawa, Kentaroh Miyoshi, Hiromasa Yamamoto, Mikio Okazaki, Shinichi Toyooka