Hyaluronic Acid Based Azo Polymer: Synthesis, Characterization, and Photo‐Responsiveness

Abstract

Hyaluronic acid based azo polymer (HA‐Azo‐COOH) is synthesized by post‐azo coupling reaction. Controllable grafting percent of azobenzene pendant is achieved by adjusting the feed ratio. In selective solvents (dimethyl sulfoxide/water), uniform colloidal aggregates of the prepared polymer can be obtained by self‐assembly process. The self‐assembled colloids can be elongated along the polarization direction of the irradiation laser light. The relationship between the deformation of colloids and the irradiation time is explored.