DOI: 10.1158/1078-0432.ccr-23-1955 ISSN:

Genomic Portraits: Reflections into a tumor's response to therapy

Susan F. Slovin
  • Cancer Research
  • Oncology
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Abstract

Well-annotated matched tissue specimens both prior to and after initiation of androgen receptor signaling inhibitors (ARSIs) have revealed activation of unique signaling pathways and genomic signatures that identify a profile to guide therapy. A recent study represents the largest prospective biospecimen banking protocol to study mechanisms of resistance to ARSIs.

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