DOI: 10.1039/d3cc05536a ISSN: 1359-7345
Engineered fluorogenic HaloTag ligands for turn-on labelling in live cells
Bryan J. Lampkin, Joshua A. Kritzer- Materials Chemistry
- Metals and Alloys
- Surfaces, Coatings and Films
- General Chemistry
- Ceramics and Composites
- Electronic, Optical and Magnetic Materials
- Catalysis
Fluorogenic dyes enable wash-free turn-on fluorescent readouts. Here, we report novel fluorogenic HaloTag benzothiadiazole dyes for cellular imaging by optimizing for both dye brightness and low background in cells.