DOI: 10.1002/chem.202303545 ISSN: 0947-6539
Electrophilic Fluorination of Silyl Dienol Ethers: a General and Selective Access to γ‐Fluoro Enals
Yang Li, Marina Briand, Karinne Miqueu, Elsa Anselmi, Emmanuel Magnier, Guillaume Dagousset- General Chemistry
- Catalysis
- Organic Chemistry
We describe the direct synthesis of γ‐fluoro enals from the corresponding silyl dienol ethers. This simple process operates under mild conditions and is compatible with a wide range of functionalities. The high γ regioselectivity of this protocol was rationalized by means of theoretical calculations