DOI: 10.3390/m1790 ISSN: 1422-8599


Bakr F. Abdel-Wahab, Hanan A. Mohamed, Benson M. Kariuki, Gamal A. El-Hiti
  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

The reaction of a mixture of equimolar quantities of 2-acetylbenzofuran and (2,4,6-trichlorophenyl)hydrazine in ethanol containing concentrated hydrochloric acid (0.2 mL; 37%) as a catalyst under reflux for two hours yielded 1-(1-(benzofuran-2-yl)ethylidene)-2-(2,4,6-trichlorophenyl)hydrazine. The crude product was purified by crystallization using dimethylformamide to provide the title heterocycle in a 90% yield. The structure of the new heterocycle was confirmed through X-ray diffraction and spectral analyses.

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