DOI: 10.1039/d3na00918a ISSN: 2516-0230
Development of a protocol of isolation of nanoparticles from patients' broncho-alveolar lavages for their in vitro toxicity assessment
Kévin Bernal, Ozge Kose, Lara Leclerc, Jean-Michel Vergnon, Jérémie Pourchez, Valérie Forest- General Engineering
- General Materials Science
- General Chemistry
- Atomic and Molecular Physics, and Optics
- Bioengineering
Objective: assessment of the toxicity of particles contained in broncho-alveolar lavages (BAL) from patients. Issue: BAL are conditioned in sodium hypochlorites solution ⇒ cannot be directly incubated with cells. Solution: 2 proposed approaches.