DOI: 10.1039/d3ra07201k ISSN: 2046-2069

Development of a green, concise synthesis of nicotinamide derivatives catalysed by Novozym® 435 from Candida antarctica in sustainable continuous-flow microreactors

Zhi-Kai Sheng, Yi Liu, Li-Hua Du, Shi-Yi Zhang, Ao-Ying Zhang, Han-Jia Xie, Hang Lin, Bing-Lin Yan, Miao-Miao Xue, Zhi-Xuan Ruan, Guo-Neng Fu, Bing-Le Pan, Tong-Yao Zhou, Xi-Ping Luo
  • General Chemical Engineering
  • General Chemistry

A continuous production of nicotinamide derivatives was performed for the first time by exploiting the continuous-flow microreactors coupled with enzymes.

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