DOI: 10.1039/d3md00693j ISSN: 2632-8682

Design, synthesis and biological evaluation of novel morpholinopyrimidine-5-carbonitrile derivatives as dual PI3K/mTOR inhibitors

Ghada S. Rady, Moshira A. El Deeb, Marwa T. M. Sarg, Azza T. Taher, Amira A. Helwa
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science
  • Pharmacology
  • Molecular Medicine
  • Biochemistry

In this study, novel morpholinopyrimidine-5-carbonitriles were designed and synthesized as dual PI3K/mTOR inhibitors and apoptosis inducers.

More from our Archive