DOI: 10.1039/d3ra08127c ISSN: 2046-2069
DBU-catalyzed diastereoselective 1,3-dipolar [3+2] cycloaddition of trifluoroethyl amine-derived isatin ketimines with chalcones: synthesis of 5′-CF3-substituted 3,2′-pyrrolidinyl spirooxindoles
Feng-Ji Zhou, Bao-Lei Zhu, Zhen-Hui Huang, Ning Lin, Zhen-Wei Zhang- General Chemical Engineering
- General Chemistry
A diastereoselective 1,3-dipolar cycloaddition reaction between trifluoroethyl amine-derived isatin ketimines and chalcones was successfully achieved in the presence of DBU.