DOI: 10.52711/0974-360x.2024.00079 ISSN: 0974-360X

Correlation Serum Vitamin D with Level of control of Childhood Asthma

Abdul Haseeb Mohammed, Akhmedov Jobir Mokhirjonovich, Ismailova Rushana Nurbekovna, Mirzayeva Malika Faxriddin Qizi, Khakimova Dilyora Ulugnekovna
  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Background: Childhood asthma is the most prevalent chronic condition in children, and it, like many other chronic illnesses, has a significant impact on the social and emotional life of children and their families. Objectives: To study the correlation of Serum Vitamin D With Level Of Control Of Childhood Asthma. Methods: A comprehensive clinical history was taken, including the child's dietary patterns and the amount of hours spent outside during the day to assess the child's exposure to sunshine. An evaluation of the respiratory system was carried out. The child's nutritional status was determined using WHO growth charts. Diagnostic investigations like Chest x-ray, complete blood count (CBC), erythrocyte sedimentation rate (ESR), absolute eosinophil count (AEC), nasal smear cytology, Peak Expiratory Flow Rate (PEFR), and spirometry were all performed. Results: A total of 150 children with Asthma were divided into groups based on severity, The Intermittent (n=34), mild persistent (n=93), moderate persistent (n=23) and severe persistent (n=0), Since there was no case classified in the severe persistent group only 3 groups were classified. Intermittent: Out of 34 children having intermittent asthma severity, Vitamin- D was deficient in 35.29% of the cases, Insufficient in 17.64% of the cases, Sufficient in 47% of the cases. Mild Persistent: Out of 93 children having mild persistent asthma severity, Vitamin- D was deficient in 58% of the cases, Insufficient in 19.35% of the cases, Sufficient in 22.58% of the cases. Moderate Persistent: Out of 23 children having moderate persistent asthma severity, Vitamin-D was deficient in 56.5% of the cases, Insufficient in 17.39% of the cases, Sufficient in 26% of the cases. Conclusion: Asthmatics have a significant prevalence of Vitamin D deficiency and insufficiency. Although there was no significant relationship between asthma severity and Vitamin D levels, low Vitamin D levels were correlated to a protracted duration of illness and a larger proportion of exacerbations, suggesting that Vitamin D may have a role in asthma exacerbations.

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