Comparison of Structural and Functional Features in Primary Angle-Closure and Open-Angle Glaucomas
Jessica A. Sun, Melissa Yuan, Grace E. Johnson, Louis R. Pasquale, Michael V. Boland, David S. Friedman, Tobias Elze, Lucy Q. Shen, Mengyu Wang- Ophthalmology
Precis:
Using a large dataset, we showed structural and functional differences between primary angle closure glaucoma and primary open angle glaucoma. Primary angle closure glaucoma has relative structural preservation and worse functional loss inferiorly.
Purpose:
To identify structural and functional differences in primary angle-closure glaucoma (PACG) and primary open-angle glaucoma (POAG).
Patients and Methods:
In this large cross-sectional study, differences in structural and functional damage were assessed among POAG and PACG patients with optical coherence tomography and reliable visual field testing.
Results:
283 PACG and 4,110 POAG patients were included. Despite similar mean deviation on visual fields (mean [standard deviation] –7.73 [7.92] vs. –7.53 [6.90] dB,
Conclusions:
PACG patients had less structural damage than POAG patients despite similar degrees of functional loss. Regional differences in patterns of functional and structural loss between POAG and PACG may improve disease monitoring for these glaucoma subtypes.