DOI: 10.1002/adsc.202301169 ISSN: 1615-4150
Catalytic Deoxygenative Reduction of Hydrazides to Hydrazines via B(C6F5)3‐Catalyzed Hydrosilylation
Lijin Xu, Heyu Wang, Ji Yang, Zhen Li Luo, Zhen Yao, Jianbo Yang, Huanrong Li- General Chemistry
Abstract: The catalytic deoxygenative reduction of hydrazides to the corresponding alkyl hydrazine with PhSiH3 via B(C6F5)3‐catalyzed hydrosilylation is reported. This metal‐free protocol is compatible with various acylhydrazides and diacylhydrazides, giving rise to a variety of structurally diverse alkyl hydrazine products in 63‐95% yields. The proper selection of borane catalyst and hydrosilane reductant is essential for catalysis. Mechanistic investigations reveal that the reaction involves a hydrazone intermediate.