DOI: 10.1063/1.1746492 ISSN:
Calculation of Equilibrium Constants for Isotopic Exchange Reactions
Jacob Bigeleisen, Maria Goeppert Mayer- Physical and Theoretical Chemistry
- General Physics and Astronomy
It is pointed out that the possibility of chemical separation of isotopes is a quantum effect. This permits a direct calculation of the difference in the free energies of two isotopic molecules. Tables and approximation methods are given which permit a rapid calculation of equilibrium constants if the frequency shifts on isotopic substitution are known. Several applications are discussed.