DOI: 10.4103/bbrj.bbrj_251_23 ISSN: 2588-9834

Calcium Sulfate Alone or Associated with Chorion Membrane in Deep Narrow Periodontal Defect? A Clinical and Radiographic Study

Anjusha Sharda, SK Aziz Ikbal, Neelu Verma, Sanjay Gupta, Zeba Rahman Siddiqui
  • Biotechnology



Soft-tissue intervention over bony defects may impede periodontal regeneration, the sole purpose of periodontal therapy. Human chorion membrane (CM) enhances guided tissue regeneration (GTR) and restores lost tissue. Consequently, calcium sulfate may represent a promising class of bone graft substitutes that helps in significant attachment gain without GTR membrane in deep narrow defects. Hence, this study was conducted to evaluate the efficacy of calcium sulfate graft in periodontal regeneration and to weigh the rationale of using CM for GTR in deep narrow defects.


Thirteen patients with bilateral deep narrow defects clinically and radiographically (26 sites, ≥7 mm pocket depth [PD]) were selected and randomly allocated to Group I (open flap debridement and calcium sulfate placement) and Group II (open flap debridement and calcium sulfate with CM placement). Clinical parameters such as PD, clinical attachment level, and radiographical intrabony defect were recorded at baseline and 6 months postsurgery.


Significant attachment gain was found in both groups with nonsignificant intergroup differences.


Calcium sulfate with or without CM is able to restore deep narrow bony defects efficiently. Deep narrow defects itself able to prevent soft-tissue collapse and ascertain excellent periodontal regeneration.

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