DOI: 10.1083/jcb.202403003 ISSN: 0021-9525

Building the centrosome: PLK-1 controls multimerization of SPD-5

Paul Conduit
  • Cell Biology

Centrosome maturation relies on the assembly of an underlying molecular scaffold. In this issue of JCB, Rios et al. ( use cross-linking mass spectrometry to reveal how PLK-1 phosphorylation promotes intermolecular SPD-5 self-association that is essential for scaffold formation.

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