Association of eGFR with stages of diabetic retinopathy and age-related macular degeneration in Indian population
Vidya Neelamegam, R Janani Surya, Praveena Venkatakrishnan, Tarun Sharma, Rajiv Raman- Ophthalmology
Purpose:
To investigate the influence of glomerular filtration rate in renal disease decline and its association with diabetic retinopathy (DR) and age-related macular degeneration (ARMD) in patients in South India.
Methods:
A population-based cross-sectional study was conducted including participants with DR and ARMD recruited from urban and rural populations. The data collection included medical history, anthropometric measurements, and ophthalmic work-up. The estimated glomerular filtration rate (eGFR) was calculated using the equation of chronic kidney disease-epidemiology collaboration (CKD-EPI). The grading of AMD was done by a single experienced (more than 5 years) vitreoretinal surgeon as per the International ARM Epidemiological Study Group and it was staged based on grading in the worsened eye.
Results:
A decline in eGFR was observed as the severity of DR increased (
Conclusion:
Reduced eGFR values were associated with an increase in the severity of DR and ARMD.