DOI: 10.1039/d3ob01147j ISSN: 1477-0520
Aryne and CO2-based formal [2 + 2 + 2] annulation to access tetrahydroisoquinoline-fused benzoxazinones
Shiqi Liu, Kun Zhang, Yutong Meng, Jiaxi Xu, Ning Chen- Organic Chemistry
- Physical and Theoretical Chemistry
- Biochemistry
A three-component formal [2 + 2 + 2] annulation has been described from 3,4-dihydroisoquinolines, CO2, and benzynes, accessing tetrahydroisoquinoline-fused benzoxazinones in moderate to excellent yields.