DOI: 10.13005/ojc/390623 ISSN: 2231-5039

Anti-Oxidant Activities, Dosage of Total Polyphenols and Flavonoids from Crossopteryx febrifuga (AFZ. Ex G. Don) Benth (Rubiaceae)

Mbaïhougadobé Séverin, Madjitoloum Bétoloum Salomon, Mihaela Cudalbeanu, Mbaïogaou Abel, Bianca Furdui, Rodica Mihaela Dinică
  • Drug Discovery
  • Environmental Chemistry
  • Biochemistry
  • General Chemistry

The aim of this study was to determine the total polyphenols and flavonoids in extracts of Crossopteryx febrifuga (AFZ. Ex G. Don) Benth (CF) and to evaluate their antioxidant activity. TLC also reveals the presence of free phenolic acids, flavonoids. Determination of these compound families in the extracts yielded high levels of polyphenols and flavonoids in ethyl acetate extracts, with polyphenols at 264.233 mg and flavonoids at 111.784 mg. the qualitative method for determining antioxidant activity using the DPPH TLC method, gives yellow streaks indicating activity. The ethyl acetate extract showed greater inhibition than the other two extracts with the two radicals used. The extracts inhibited the DPPH radical at 35 min and ABST at 120 min. The results obtained would justify the use of this plant species in traditional medicine in Chad.

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