An Analysis of Scoliosis in Autism Spectrum Disorder
Keith Orland, Kaela Harvey, Lydia N. Klinkerman, Arturo Corrales, Adam Jamnik, Connor Zale, Chan-Hee Jo, Karl Rathjen, Amy McIntosh, Jason Petrasic, Daniel J. Sucato, Brandon Ramo, Megan Johnson, Jaysson T. Brooks- Orthopedics and Sports Medicine
- General Medicine
- Pediatrics, Perinatology and Child Health
Background:
Children with autism/Asperger are grouped into the diagnosis of autism spectrum disorder (ASD). It remains uncertain whether children with ASD and scoliosis have radiographic and clinical outcomes similar to idiopathic scoliosis (IS) patients.
Methods:
A single-center, retrospective review of a prospective scoliosis registry evaluated patients who had a posterior spinal fusion±Anterior Spinal Fusion and an underlying diagnosis of ASD between 1990 and 2021. A 2:1 match with AIS patients by age and sex was compared using demographic, radiographic, intraoperative, and SRS-22/30 variables.
Results:
Thirty patients with ASD (63% male, mean age at surgery 14.6±2.5 y) met inclusion criteria, with a follow-up of 2.46±1.00 years. Despite no differences in curve magnitude preoperatively, patients with ASD had a higher percent correction at 2-year follow-up (66% vs. 57%,
Conclusions:
Although patients with ASD exhibited decreased lordosis compared with IS patients preoperatively, their radiographic outcomes at 2-year follow-up were the same. In addition, ASD patients maintained greater curve correction than IS patients at 2 years follow-up.
Level of Evidence:
Prognostic retrospective study.