Dnyanda Kangude, S. D. Mankar

A Review on Biosimilar – A Medicine from the Life and for the Life

The medicine that is very close in structure and function to biological drugs. Biological drugs are the drugs made from proteins or are piece of proteins. They are naturally or artificially unlike other drugs. Biological drug must be made in living system like yeast, bacteria or animal cells using biotechnology tools. As drug, biologic have several advantages over small molecule. Biologics are very target – specific and their side – effects are mostly related to exaggerated pharmacological effect. Whereas small molecule are more prone to induce harmful non - target effect. Manufacturing a biologic consist of genetically modifying a cell, which become the basis for a cell line used for the production of the necessary protein for biologic medicine. As per the evaluated report of pharm use of biosimilar contributing to 50% of top pharma sales by 2022. Biosimilar are approved according to their safety, quality and efficacy which is apply to all biological medicine. Biosimilar are highly similar to biological medicine.

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