DOI: 10.1002/jgf2.646 ISSN:

A case of mild encephalitis associated with COVID‐19

Kentaro Nagae, Mizuki Haraguchi, Takashi Sakoh, Keiko Ishida, Sho Ogura, Masayo Katoh‐Morishima, Hideki Araoka
  • Family Practice
  • Geriatrics and Gerontology
  • Internal Medicine


We report a case of mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) in a 31‐year‐old man. He had been diagnosed with mild COVID‐19 3 days earlier and presented to the emergency department with altered mental status. Brain magnetic resonance imaging (MRI) showed a high‐intensity area confined to the splenium of the corpus callosum on diffusion‐weighted imaging, which is consistent with MERS. MERS is characterized by a reversible change in the splenium of the corpus callosum. MERS secondary to COVID‐19 has been reported recently. It is important to consider MERS in COVID‐19 patients with impaired consciousness.

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