Habous Dr. Mohamad, Khattak Dr. Ahmed, Muir Gordon

(189) INVESTIGATING THE RISK FACTORS OF PENILE ARTERIAL INSUFFICIENCY AND VENO-OCCLUSIVE DYSFUNCTION IN PATIENTS WITH ERECTILE DYSFUNCTION

  • Urology
  • Reproductive Medicine
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Psychiatry and Mental health
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Abstract Objectives penile arterial insufficiency (PAI) is a known cause of erectile dysfunction (ED). It was reported that a more generalized peripheral atherosclerotic process is associated with a severer PAI, and this in turn was correlated well with decreased blood supply in more important arteries like the coronary and carotid arteries. We investigated the risk factors for PAI. Methods Patients who attended our urology clinic complaining of ED for more than 6 months, were prospectively enrolled in this study in one year period. Patient consent was taken and ethical committee approval. Complete medical history and thorough general and local examination including body mass index (BMI), Peyronie’s disease (PD) and penile size measurements (length and girth) were done for all of them. Laboratory tests included testosterone, lipid profile, and glycated haemoglobin (HbA1c). Penile duplex ultrasound study (PDU) was done for all patients after intra-cavernosal injection (ICI) with Alprostadil. peak systolic velocity (PSV) and end diastolic velocity (EDV) were measured after 15 minutes. Results Patients who attended our clinic complaining of ED for more than 6 months, were prospectively enrolled in this study in one year period. Patient consent was taken and ethical committee approval. Complete medical history and thorough general and local examination including body mass index (BMI), Peyronie’s disease (PD) and penile size measurements (length and girth) were done for all of them. Laboratory tests included testosterone, lipid profile, and glycated haemoglobin (HbA1c). Penile duplex ultrasound study (PDU) was done for all patients after intra-cavernosal injection (ICI) with Alprostadil. peak systolic velocity (PSV) and end diastolic velocity (EDV) were measured after 15 minutes. Conclusions Aging, tobacco consumption, DM and hypertension seem to have a negative impact on penile hemodynamics, which was statistically significant. In our patients, there was no statistically significant effect on penile hemodynamics in patients with increased BMI, low testosterone, PD or according to penile size Conflicts of Interest None

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