Pozzi Dr. Edoardo, Bertini Dr. Alessandro, Fallara Dr. Giuseppe, Belladelli Dr. Federico, Cilio Dr. Simone, Raffo Dr. Massimiliano, Negri Fausto, Cella Ludovica, Fantin Margherita, Corsini Dr. Christian, Lanzaro Dr. Francesco, Candela Dr. Luigi, Capogrosso Dr. Paolo, Boeri Dr. Luca, d'Arma Dr. Alessia, Montorsi Prof. Francesco, Salonia Prof. Andrea

(141) DETAILED CHARACTERISATION OF PATIENTS UNDERGOING DYNAMIC PENILE COLOR DOPPLER DUPLEX ULTRASOUND FOR ERECTILE DYSFUNCTION – FINDINGS FROM A REAL-LIFE CROSS-SECTIONAL STUDY

  • Urology
  • Reproductive Medicine
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Psychiatry and Mental health
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Abstract Objectives Dynamic penile Color Doppler Duplex Ultrasound (CDDU) is an effective tool to assess of men with vasculogenic erectile dysfunction (ED). We aimed to describe clinical and sociodemographic characteristics of men with parameters suggestive of normal vs. arteriogenic ED at CDDU, and to identify potential predictors of arteriogenic ED at CDDU. Methods Complete data of 245 consecutive patients undergoing CDDU for ED were analysed. Comorbidities were scored using the Charlson comorbidity index (CCI). All patients completed the International Index of Erectile Function (IIEF) at baseline. Serum hormones were dosed for every patient. CDDU was performed after intracavernosal injection of Alprostadil 20 microGr. Arteriogenic ED was defined with a peak systolic velocity (PSV) <35cm/s at CDDU. Patients with deficient veno-occlusive mechanisms were excluded from the analyses. Patients were divided into with normal parameter vs. parameters suggestive for arteriogenic ED at CDDU. Descriptive statistics compared the clinical and sociodemographic characteristics of the two groups. Logistic regression models explored the potential predictive factors of arteriogenic ED at CDDU. Results Overall, median (IQR) age was 53 (42-60) yr and right/left PSV were 42.3(32.4-55.1) and 42.4(31.9-54.1) cm/s respectively. Of all, 81 (33.1%) had arteriogenic ED at CDDU. Patients with arteriogenic ED were older (59vs.50yr, p<0.001), had higher BMI (26.54vs.25.12 kg/m2, p=0.005), higher rates of CCI≥1 (64.2%vs. 43.9%, p=0.006), arterial hypertension (37%vs. 19.5%, p=0.005), smoking (28%vs. 13.6%, p=0.002) but lower rates of regular physical exercise (50.6%vs. 54.9%, p=0.04) compared to patients with normal CDDU parameters. No other statistical differences were found. At multivariable logistic regression analysis, the only predictor of arteriogenic ED was age (OR: 1.07, 95%CI: 1.01-1.14, p=0.03) after adjusting for BMI, CCI≥1, arterial hypertension, severe ED, and regular physical exercise. Conclusions One out of three men undergoing CDDU for ED depict criteria suggestive of arteriogenic ED. Similar rates of severe ED were found between men with normal and pathological CDDU parameters. Older age was identified as the only predictive factor of arteriogenic ED at CDDU. Conflicts of Interest N/A

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