125-LB: Risk of Hypoglycemia as Measured by Continuous Glucose Monitoring in the Hospital Setting—An Observational Study

Background: Prospective studies investigating the occurrence of and risk factors for continuous glucose monitoring (CGM) detected hypoglycemia in the inpatient setting are limited.

Methods: In this prospective observational study, patients hospitalized on medical and surgical floors and undergoing fingerstick glucose monitoring wore blinded Dexcom G6Pro sensors. Participants with sensor readings <54mg/dL were identified after excluding erroneous readings from compression via manual review. Data from participant survey and chart review were analyzed chi square tests for categorical variables, and t test and Kruskal-Wallis test for continuous variables to identify predictors of hypoglycemia.

Results: CGM data were collected from 268 participants. At least one episode of CGM glucose <54 mg/dL occurred in 30 (11%). Participants with at least one episode of glucose <54mg/dL had longer hospital stay, lower A1c (but also lower hemoglobin level), and were more likely to have type 1 diabetes compared to those without hypoglycemia (Table 1). Forty-six (17%) had what appeared to be a false reading <70 mg/dL due to compression or artifact at least once.

Conclusion: CGM may be helpful in identifying hypoglycemia in hospitalized patients. Further research is needed to identify patient populations who may benefit from inpatient CGM monitoring for prevention of hypoglycemia.