DOI: 10.1097/inf.0000000000004347 ISSN: 0891-3668
Use of Cefiderocol in the Management of Children With Infection or Colonization With Multi-drug Resistant Gram-negative Bacteria: A Retrospective, Single-center Case Series
Hanna Schmid, Li-An K. Brown, Bairavi Indrakumar, Orlagh McGarrity, James Hatcher, Alasdair Bamford- Infectious Diseases
- Microbiology (medical)
- Pediatrics, Perinatology and Child Health
Cefiderocol, a novel siderophore cephalosporin, represents a treatment option for infections with multidrug-resistant Gram-negative bacteria, of which rates are rising worldwide. Clinical data on its use in children is limited. In our pediatric case series, the largest reported to date, cefiderocol seems safe and well tolerated, with more favorable clinical outcomes when compared to the literature reviewing adult cases.