Uncommon Variant of Ameloblastoma Presenting in the Right Mandibular Body-Acanthomatous Type in a 49-year-old Female: A Case Report

The following case report elaborates on the case of a 49-year-old female who has been experiencing swelling on the right side of her lower jaw for the last 7–8 months. Ameloblastoma is the most frequent tumor that develops from the remaining odontogenic epithelium in the oral cavity. This multicystic ameloblastoma was diagnosed on OPG, confirmed by histopathology, and was managed by enucleation of the tumor. Characteristic radiographic features evident in the present case were large multilocular radiolucency, well-defined margins, soap bubble appearance, thinning of the inferior cortex of the mandible with expansion, window formation, loss of the external oblique ridge, and root resorption. Histologic photomicrograph shows squamous metaplasia and keratin formation occurring in the central stellate-reticulum-like cells, odontogenic epithelial islands with peripheral palisading of columnar cells, and central squamous metaplasia, histopathologically suggestive of Acanthomatous ameloblastoma. Patient was treated with enucleation of the tumor, peripheral osteotomy, chemical cauterization with carnoy’s solution, platelet-rich fibrin application, and primary closure of the right mandibular body and ramal ameloblastoma under general anesthesia. Postoperative instructions were provided to the patient to maintain oral hygiene, follow a soft diet, follow a high-protein diet, and attend a follow-up visit after 1 week. Furthermore, the patient was kept on close periodic and long-term follow-up, and no recurrence was observed. This report’s objectives are to give a current summary of the literature on ameloblastoma and to explain the case of a middle-aged woman diagnosed with the acanthomatous variant of ameloblastoma.