DOI: 10.1039/d6tb00168h ISSN: 2050-750X
Tyrosine-capped gold nanoparticles enable cysteine-free peptide loading, enhancing the antipseudomonal efficacy of scorpion-derived AamAP1-Lys-NH 2 in a burn wound infection model
Rosalind J. Van Wyk, Mandelie van der Walt, June C. Serem, A. James Mason, Megan J. Bester, Anabella R. M. GasparTyrosine-capped AuNPs enable near-complete loading of AamAP1-Lys-NH 2 , reduce cytotoxicity and protease degradation and preserve antimicrobial activity. Nanoparticles improve survival in P. aeruginosa burn wound infections, supporting wound therapy.